The PLGA Foundation funded Dr. Charles Eberhart’s “PLGA: Dedicated Tumor Banking and Establishment of Cell Lines and Xenografts” project. A major roadblock hindering investigations into the various types of PLGA is the lack of frozen tissue or renewable tumor models such as cell lines and xenografts. This project will implement a strategy designed to harvest tissue from the majority of PLGA and other pediatric brain tumors resected at Johns Hopkins and overcome the historical barriers by 1) committing sufficient resources, including dedicated personnel, 2) more effectively integrating neurosurgery, neuropathology and neurooncology and 3) utilizing improved laboratory technologies enabling the establishment of cell lines and xenografts.
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