Through a unique international partnership between the PLGA Research Program at DFCI, the Everest Center PLGA Research Program at the German Cancer Research Center and Research Institute of the McGill University Medical Center, this newest publication summarizes The Power of Human Cancer Genetics as Revealed by Pediatric Low-Grade Glioma. In this article, Jones, Bandopadhayay and Jabado review novel diverse LGG entities, in which oncogenic processes show striking age-related neuroanatomical specificity (highlighting their close interplay with development); the opportunities they provide for targeted therapies, some of which are already practiced at the bed- side; and the challenges of implementing molecular pathology in the clinic.

Read the entire article in the Annual Review of Genetics, here