Monthly Archives: May 2007

Identification of Key Genetic and Growth Control Pathway Changes in Fibrillary Astrocytoma that Represents Potential Molecular.

May 23rd, 2007|

Principal Investigators Dr. David Gutmann and Dr. Tobey MacDonald, Washington University

This study represents a collaborative project that builds upon the 2006 BTS-funded project focused on juvenile pilocytic astrocytomas (JPAs). […]

Controlling Pilocytic Astrocytoma Growth: Effects of location, age and Telomerase

May 23rd, 2007|

Principal Investigator Dr. Jeffrey Leonard, Washington University.

This study will evaluate three growth characteristics of JPA that might offer clues for research. First, JPA is primarily a disease of childhood. […]

Development of Permanent Juvenile Pilocytic Astrocytoma Cell Lines for Preclinical Trails

May 23rd, 2007|

Principal Investigator Dr. Kwong-Kwok Wong, University of Texas M.D. Anderson Cancer Center.

This study will investigate different methods to immortalize JPA primary cells which have limited growth potential. Cell culture […]

Molecular Prognostic Markers for Low-Grade Gliomas

May 23rd, 2007|

Principal Investigator Dr. Ian F. Pollack, Children’s Hospital of Pittsburgh, University of Pittsburgh.

This study will apply the prognostic markers in childhood high-grade gliomas to analyze low-grade gliomas. We will […]

The Biologic and Prognostic Role of Replicative and Oncogene Induced Senescence

May 23rd, 2007|

Principal Investigator Dr. Uri Tabori, Hospital for Sick Children, University of Toronto.

This study will study why some PLGA tumors stop growing. Using this alternative research strategy, we will build […]

Targeting Cancer Stem Cells in Pediatric Fibrillary Astroctyoma

May 22nd, 2007|

Principal Investigator Dr. David H. Rowitch, Dr. C. David James, Dr. Graeme Hodgson, Ph.D. University of California, San Francisco

The ultimate goal of this proposal is to change the landscape […]

Establishment of PLGA Research Program

May 22nd, 2007|

Dana Farber Cancer Institute’s Pediatric Low-Grade Astrocytoma Program

May 18th, 2007|

In May 2007, the Dana Farber Cancer Institute kicked off the Pediatric Low Grade Astrocytoma Research Program, funded by an initial $2 million grant from 5 families affiliated with the […]

Dana Farber Cancer Institute Projects

May 7th, 2007|

In May 2007, the establishment of the first dedicated PLGA research program at the Dana Farber Cancer Institute. The initial $2 million grant will concentrate resources on research on […]