Principal Investigator: Ian Pollack, MD, Childrens Hospital of Pittsburgh, Pittsburgh, Pennsylvania
The prognosis for children with treatment-refactory low-grade gliomas is suboptimal, and new treatment approaches are needed that target the […]
Principal Investigator: Elizabeth Maher, MD, PhD, University of Texas Southwestern Medical Center, Dallas, Texas
Pilocytic astrocytomas (PA), the most common childhood brain tumor, is classified into 2 groups, those that […]
Principal Investigator: Xiao-Nan Li, MD, PhD, Texas Children’s Hospital-Baylor College of Medicine,
Houston, Texas
The goal of this project is to develop and characterize a panel of primary tumor-based orthotopic xenograft […]
Principal Investigator: Mark Kieran, MD, PhD, Dana-Farber Cancer Institute, Boston, Massachusetts
Low-grade gliomas are the most common brain tumor in children. While a portion of patients are effectively cured with […]
Principal Investigator: Michael K. Cooper, MD, Vanderbilt University Medical Center, Nashville, Tennessee
The intractable nature of gliomas to current chemotherapies and radiation underscores a tremendous need for improved interventions. A […]