Monthly Archives: May 2018

A Phase I/II and Target Validation Study of TAK-580 (MLN2480) for Children with Low-Grade Gliomas and Other RAS/RAF/MEK/ERK Pathway Activated Tumors

May 13th, 2018|

Principal Institutions: Dana Farber Cancer Institute in partnership with the Pacific Pediatric Neuro Oncology Consortium (PNOC).  Oncogenic dysregulation of the RAS/RAF/MEK/ERK pathway has been described in a number of diverse malignancies, […]

Critical Mechanisms of Gene Regulation in Medulloblastoma

May 13th, 2018|

Under the leadership of Dr. Miguel Rivera at Massachusetts General Hospital, this project focuses on medulloblastoma. Medulloblastoma is the most common malignant brain cancer in children and consists of […]