The following Pediatric Low Grade Astrocytoma (PLGA) related research abstracts represent the most current abstracts published on children’s brain tumors. To search for specific articles, please go to or select the article title below to be linked to the relevant research abstract.

 | Size: 736 KB Dec 15th 2019 The Power of Human Cancer Genetics as Revealed by Low-Grade Gliomas  | Size: Sep 17th 2018 Attainment of Functional and Social Independence in Adult Survivors of Pediatric CNS Tumors: A Report from the St Jude Lifetime Cohort Study  | Size: 412 KB Aug 1st 2017 Pediatric low-grade gliomas: next biologically driven steps  | Size: 50 MB Sep 15th 2017 Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways  | Size: 10 B Aug 14th 2017 CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles  | Size: 599 KB Apr 4th 2017 Immune responses and outcome after vaccination with glioma-associated antigen peptides and poly-ICLC in a pilot study for pediatric recurrent low-grade gliomas  | Size: 92 KB Jan 1st 2016 Low rates of recurrence and slow progression of pediatric pilocytic astrocytoma after gross-total resection: justification for reducing surveillance imaging  | Size: 568 KB Nov 3rd 2014 White Matter Compromise Predicts Poor Intellectual Outcome in Survivors of Pediatric Low-Grade Glioma  | Size: 1 MB Jun 22nd 2015 Mortality in Children with Optic Pathway Glioma Treated with Up-Front BB-SFOP Chemotherapy  | Size: 180 KB Feb 5th 2015 BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma  | Size: 433 KB Jun 2nd 2014 Quality of life outcomes in proton and photon treated pediatric brain tumor survivors  | Size: 156 B Apr 1st 2013 Incidence of Second Malignancies Among Patients Treated With Proton Versus Photon Radiation  | Size: 747 KB Feb 20th 2014 Pediatric Low-Grade Gliomas: How Modern Biology Reshapes the Clinical Field  | Size: 3 MB Jan 30th 2014 ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the GlioblastomaTumor-Initiating Cell State  | Size: 4 MB Mar 17th 2014 Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition  | Size: 10 B Jul 1st 2011 Long-term clinical outcomes following treatment of childhood craniopharyngioma  | Size: 10 B Aug 1st 2013 Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma  | Size: 10 B Sep 1st 2013 Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy  | Size: 10 B Jul 23rd 2013 New Strategies in Pediatric Gliomas: Molecular Advances in Pediatric Low-Grade Gliomas as a Model  | Size: 10 B Dec 2nd 2013 BET-bromodomain inhibition of MYC-amplified Medulloblastoma  | Size: 332 KB Feb 12th 2014 Long-Term Outcome- Pediatric Low-Grade Gliomas: Surveillance Epidemiology and End Results  | Size: 10 B Dec 10th 2013 Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study  | Size: 10 B Jan 1st 2003 Long-term survival in children under 3 years of age with low-grade astrocytoma  | Size: 10 B Mar 1st 2007 Optic Pathway Gliomas in Neurofibromatosis-1: Contraversies and Recommendations  | Size: 10 B Aug 1st 2007 Presentation of Childhood CNS tumours: A Systematic Review and Meta-analysis  | Size: 10 B Sep 1st 2007 Dose intensive chemotherapy to treat progressive low-grade gliomas in children, phase 2  | Size: 10 B Sep 1st 2007 Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1  | Size: 10 B Sep 1st 2007 Magnetic resonance imaging and spectroscopy of pilomyxoid astrocytomas: case reports and comparison with pilocytic astrocytomas  | Size: 10 B Oct 1st 2007 Advanced Magnetic Resonance Imaging and Metabolic Studies of Low-Grade Gliomas of Childhood  | Size: 10 B Nov 1st 2007 Angiocentric glioma: report of clinico-pathologic and genetic findings in 8 cases  | Size: 10 B Nov 1st 2007 Temozolomide in pediatric low-grade glioma  | Size: 10 B Dec 1st 2007 Carboplatin hypersensitivity reaction in pediatric patients with low-grade glioma: a Canadian Pediatric Brain Tumor Consortium experience  | Size: 10 B Dec 1st 2007 Optic pathway gliomas: a review  | Size: 10 B Jan 1st 2008 Juvenile pilocytic astrocytomas do not undergo spontaneous malignant transformation: grounds for designation as hamartomas  | Size: 10 B May 1st 2008 Disease Information – Brain Tumor: Astrocytoma / Glioma  | Size: 10 B Nov 1st 2008 Tandem Duplication Producing a Novel Oncogenic BRAF Fusion Gene Defines the Majority of Pilocytic Astrocytomas  | Size: 10 B Jun 1st 2009 Long-Term Outcomes Among Adult Survivors of Childhood CNS Malignancies in the Childhood Cancer Survivor Study  | Size: 10 B Sep 1st 2009 Impact of Morphology, MIB-1 and MGMT on Outcome in Pilocytic Astrocytomas  | Size: 10 B Nov 1st 2011 A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53  | Size: 410 KB Nov 23rd 2013 Mass spectrometry imaging as a tool for surgical decision-making  | Size: 4 MB Oct 4th 2013 Molecular imaging of drug transit through the blood-brain barrier with MALDI imaging  | Size: 1 MB Sep 29th 2013 Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities  | Size: 4 MB Sep 4th 2013 Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy  | Size: 854 KB Aug 15th 2013 Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma  | Size: 1 MB Jul 18th 2013 Activation of mTORC1/mTORC2 signaling reveals mTOR as a therapeutic target  | Size: 2 MB Apr 20th 2013 Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas  | Size: 1 MB Apr 12th 2013 Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas  | Size: 2 MB Mar 28th 2013 Genomic analysis of diffuse pediatric low-grade gliomas  | Size: 976 KB Dec 5th 2012 Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors  | Size: 2 MB Jan 5th 2012 BRAF Alterations in Primary Glial and Glioneuronal Neoplasms of the Central Nervous System  | Size: 319 KB Nov 5th 2011 Favorable Outcome With Conservative Treatment for Children With Low Grade Brainstem Tumors  | Size: 15 KB Aug 1st 2011 Scientists at Cambridge University have made a major breakthrough researching brain tumours in children  | Size: 540 KB Jun 1st 2011 BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model  | Size: 2 MB May 24th 2011 Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas  | Size: 494 KB May 24th 2011 Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma  | Size: 2 MB Apr 5th 2011 New Mouse Model for PLGA on the Horizon  | Size: 540 KB Mar 5th 2011 BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications  | Size: 340 KB Feb 6th 2011 Are adult tumors REALLY different than kids?  | Size: 166 KB Oct 5th 2010 Feasibility and Efficacy of Repeated Chemotherapy for Progressive Pediatric Low-Grade Gliomas  | Size: 442 KB Sep 22nd 2010 A Multivariate Analysis of Factors Determining Tumor Progression in Childhood Low Grad Glioma  | Size: 142 KB Feb 5th 2010 Anaplasia in Pilocytic Astrocytoma Predicts Aggressive Behavior  | Size: 378 KB Sep 5th 2009 Survival and functional outcome of childhood spinal cord low-grade gliomas  | Size: 526 KB Jul 5th 2009 Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours  | Size: 300 KB Jan 5th 2009 Pediatric low-grade gliomas and the need for new options for therapy
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New medical literature is published regularly. If there is something new that you believe would be relevant and of interest to the pediatric brain tumor community, please let us know at [email protected]. Rev. 1/6/16