The following Pediatric Low Grade Astrocytoma (PLGA) related research abstracts represent the most current abstracts published on children’s brain tumors. To search for specific articles, please go to http://www.biomedsearch.com/ or select the article title below to be linked to the relevant research abstract.
| Size: 412 KB Aug 1st 2017 Pediatric low-grade gliomas: next biologically driven steps | Size: 50 MB Sep 15th 2017 Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways | Size: 10 B Aug 14th 2017 CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles | Size: 599 KB Apr 4th 2017 Immune responses and outcome after vaccination with glioma-associated antigen peptides and poly-ICLC in a pilot study for pediatric recurrent low-grade gliomas | Size: 92 KB Jan 1st 2016 Low rates of recurrence and slow progression of pediatric pilocytic astrocytoma after gross-total resection: justification for reducing surveillance imaging | Size: 568 KB Nov 3rd 2014 White Matter Compromise Predicts Poor Intellectual Outcome in Survivors of Pediatric Low-Grade Glioma | Size: 1 MB Jun 22nd 2015 Mortality in Children with Optic Pathway Glioma Treated with Up-Front BB-SFOP Chemotherapy | Size: 180 KB Feb 5th 2015 BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma | Size: 433 KB Jun 2nd 2014 Quality of life outcomes in proton and photon treated pediatric brain tumor survivors | Size: 156 B Apr 1st 2013 Incidence of Second Malignancies Among Patients Treated With Proton Versus Photon Radiation | Size: 747 KB Feb 20th 2014 Pediatric Low-Grade Gliomas: How Modern Biology Reshapes the Clinical Field | Size: 3 MB Jan 30th 2014 ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the GlioblastomaTumor-Initiating Cell State | Size: 4 MB Mar 17th 2014 Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition | Size: 10 B Jul 1st 2011 Long-term clinical outcomes following treatment of childhood craniopharyngioma | Size: 10 B Aug 1st 2013 Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma | Size: 10 B Sep 1st 2013 Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy | Size: 10 B Jul 23rd 2013 New Strategies in Pediatric Gliomas: Molecular Advances in Pediatric Low-Grade Gliomas as a Model | Size: 10 B Dec 2nd 2013 BET-bromodomain inhibition of MYC-amplified Medulloblastoma | Size: 332 KB Feb 12th 2014 Long-Term Outcome- Pediatric Low-Grade Gliomas: Surveillance Epidemiology and End Results | Size: 10 B Dec 10th 2013 Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study | Size: 10 B Jan 1st 2003 Long-term survival in children under 3 years of age with low-grade astrocytoma | Size: 10 B Mar 1st 2007 Optic Pathway Gliomas in Neurofibromatosis-1: Contraversies and Recommendations | Size: 10 B Aug 1st 2007 Presentation of Childhood CNS tumours: A Systematic Review and Meta-analysis | Size: 10 B Sep 1st 2007 Dose intensive chemotherapy to treat progressive low-grade gliomas in children, phase 2 | Size: 10 B Sep 1st 2007 Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1 | Size: 10 B Sep 1st 2007 Magnetic resonance imaging and spectroscopy of pilomyxoid astrocytomas: case reports and comparison with pilocytic astrocytomas | Size: 10 B Oct 1st 2007 Advanced Magnetic Resonance Imaging and Metabolic Studies of Low-Grade Gliomas of Childhood | Size: 10 B Nov 1st 2007 Angiocentric glioma: report of clinico-pathologic and genetic findings in 8 cases | Size: 10 B Nov 1st 2007 Temozolomide in pediatric low-grade glioma | Size: 10 B Dec 1st 2007 Carboplatin hypersensitivity reaction in pediatric patients with low-grade glioma: a Canadian Pediatric Brain Tumor Consortium experience | Size: 10 B Dec 1st 2007 Optic pathway gliomas: a review | Size: 10 B Jan 1st 2008 Juvenile pilocytic astrocytomas do not undergo spontaneous malignant transformation: grounds for designation as hamartomas | Size: 10 B May 1st 2008 Disease Information – Brain Tumor: Astrocytoma / Glioma | Size: 10 B Nov 1st 2008 Tandem Duplication Producing a Novel Oncogenic BRAF Fusion Gene Defines the Majority of Pilocytic Astrocytomas | Size: 10 B Jun 1st 2009 Long-Term Outcomes Among Adult Survivors of Childhood CNS Malignancies in the Childhood Cancer Survivor Study | Size: 10 B Sep 1st 2009 Impact of Morphology, MIB-1 and MGMT on Outcome in Pilocytic Astrocytomas | Size: 10 B Nov 1st 2011 A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53 | Size: 410 KB Nov 23rd 2013 Mass spectrometry imaging as a tool for surgical decision-making | Size: 4 MB Oct 4th 2013 Molecular imaging of drug transit through the blood-brain barrier with MALDI imaging | Size: 1 MB Sep 29th 2013 Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities | Size: 4 MB Sep 4th 2013 Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy | Size: 854 KB Aug 15th 2013 Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma | Size: 1 MB Jul 18th 2013 Activation of mTORC1/mTORC2 signaling reveals mTOR as a therapeutic target | Size: 2 MB Apr 20th 2013 Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas | Size: 1 MB Apr 12th 2013 Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas | Size: 2 MB Mar 28th 2013 Genomic analysis of diffuse pediatric low-grade gliomas | Size: 976 KB Dec 5th 2012 Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors | Size: 2 MB Jan 5th 2012 BRAF Alterations in Primary Glial and Glioneuronal Neoplasms of the Central Nervous System | Size: 319 KB Nov 5th 2011 Favorable Outcome With Conservative Treatment for Children With Low Grade Brainstem Tumors | Size: 15 KB Aug 1st 2011 Scientists at Cambridge University have made a major breakthrough researching brain tumours in children | Size: 540 KB Jun 1st 2011 BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model | Size: 2 MB May 24th 2011 Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas | Size: 494 KB May 24th 2011 Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma | Size: 2 MB Apr 5th 2011 New Mouse Model for PLGA on the Horizon | Size: 540 KB Mar 5th 2011 BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications | Size: 340 KB Feb 6th 2011 Are adult tumors REALLY different than kids? | Size: 166 KB Oct 5th 2010 Feasibility and Efficacy of Repeated Chemotherapy for Progressive Pediatric Low-Grade Gliomas | Size: 442 KB Sep 22nd 2010 A Multivariate Analysis of Factors Determining Tumor Progression in Childhood Low Grad Glioma | Size: 142 KB Feb 5th 2010 Anaplasia in Pilocytic Astrocytoma Predicts Aggressive Behavior | Size: 378 KB Sep 5th 2009 Survival and functional outcome of childhood spinal cord low-grade gliomas | Size: 526 KB Jul 5th 2009 Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours | Size: 300 KB Jan 5th 2009 Pediatric low-grade gliomas and the need for new options for therapy