A Kids’ Brain Tumor Cure Foundation is already supporting a doctorate level scientist to create mouse models of low-grade astrocytoma and to conduct entry-level tests on these cells for drugs that may benefit children with LGAs. However, to this point all of our drug testing has been conducted on cells grown in the laboratory in plastic culture dishes. Some of these cell models (and some of the drugs we have tested in vitro) now show some promise. This grant will take the next steps in testing cell for drugs outside the culture dish.