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A Phase I Study of PLX8394 Plus Ritonavir in Children with Recurrent or Progressive BRAF Activated Gliomas

June 13th, 2018|

A Phase I Study of PLX8394 Plus Ritonavir in Children with Recurrent or Progressive BRAF Activated Gliomas

Principal Institutions: Children’s Hospital of Los Angeles in partnership with the Pediatric Brain […]

Scientific and Clinical PLGA Progress: Indebted to the Founding PLGA Scientific Advisors

June 4th, 2018|

Changing the outcome for PLGA patients through cutting-edge scientific and clinical research has finally become a reality.  Thanks, in large part, to the stewardship of the 5-member PLGA Scientific […]

A Phase I/II and Target Validation Study of TAK-580 (MLN2480) for Children with Low-Grade Gliomas and Other RAS/RAF/MEK/ERK Pathway Activated Tumors

May 13th, 2018|

Principal Institutions: Dana Farber Cancer Institute in partnership with the Pacific Pediatric Neuro Oncology Consortium (PNOC).  Oncogenic dysregulation of the RAS/RAF/MEK/ERK pathway has been described in a number of diverse malignancies, […]

Critical Mechanisms of Gene Regulation in Medulloblastoma

May 13th, 2018|

Under the leadership of Dr. Miguel Rivera at Massachusetts General Hospital, this project focuses on medulloblastoma. Medulloblastoma is the most common malignant brain cancer in children and consists of […]

Phase 1 study of APX-005M CD40 agonist antibody in children and young adults with CNS tumors

January 13th, 2018|

Principal Institutions: Memorial Sloan Kettering Cancer Center and Pediatric Brain Tumor Consortium (PBTC) – This early phase, multicenter, open-label study is designed to evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, […]

December 2017: PLGA Consensus Symposium, Toronto, Canada

December 17th, 2017|

From the Perspective of a Pediatric Brain Tumor Patient

December 5th, 2017|

16 year old Sammi of Team Samantha has turned her brain tumor diagnosis at the age of 3 into an opportunity to help others. She recently spoke at TEDx […]

AKBTC Funding Helps Support 3 Recent PLGA Research Projects

November 7th, 2017|

Thanks to the ongoing support of our community, A Kids’ Brain Tumor Cure has been able to help fund a variety of PLGG research projects including the following highlighted […]

Why I PMC: Year Up “Concrete Evidence of Change”

August 7th, 2017|

AKBTC Board Member Daniel Itzkovitz, his son, Dmitri, a pediatric brain tumor survivor, and supporters discuss the crucial need for fundraising for pediatric brain tumor research. Learn more about […]

Today Show Mentions A Kids’ Brain Tumor Cure

June 26th, 2017|

The Today show mentioned AKBTC in a piece that they ran June 21, 2017 on kids helping raise awareness and funds for childhood cancer.  The article featured “Comedy Kids” […]